Antihypertensive agents reduce high blood pressure. These studies confirm Moringa oleifera's hypotensive activity.
Isolation and structure elucidation of new nitrile and mustard oil glycosides from Moringa oleifera and their effect on blood pressure. Journal of Natural Products, 57(9), 1256-1261. Faizi, S., Siddiqui, B. S., Saleem, R., Siddiqui, S., Aftab, K., & Gilani, A. U. H. (1994).
This study shows that Moringa oleifera leaves can reduce blood pressure. Their hypotensive activity is derived from isothiocyanates and thiocarbamate glycosides .
Fully acetylated carbamate and hypotensive thiocarbamate glycosides from Moringa oleifera. Phytochemistry, 38(4), 957-963. Faizi, S., Siddiqui, B. S., Saleem, R., Siddiqui, S., & Aftab, K. (1995).
This study shows that six new and three synthetically known glycosides can be isolated from the leaves of Moringa oleifera. Most of these compounds are very rare in nature. Thiocarbamates showed strong hypotensive activity.
Hypotensive constituents from the pods of Moringa oleifera. Planta medica, 64(03), 225-228. Faizi, S., Siddiqui, B. S., Saleem, R., Aftab, K., & Shaheen, F. (1998).
This study investigates the hypotensive activity of the ethanolic and aqueous extracts of Moringa oleifera whole pods and their parts, namely, coat, pulp, and seed. The activity of the ethanolic extract of both the pods and the seeds was equivalent. Thiocarbamate and isothiocyanate glycosides which were also the hypotensive principles of the pods as observed in case of Moringa leaves.
Pharmacological studies on hypotensive and spasmolytic activities of pure compounds from Moringa oleifera. Phytotherapy research, 8(2), 87-91.ISO 690 Gilani, A. H., Aftab, K., Suria, A., Siddiqui, S., Salem, R., Siddiqui, B. S., & Faizi, S. (1994).
This study shows that ethanolic extracts of Moringa oleifera leaves resulted in the isolation of four pure compounds, niazinin A (1), niazinin B (2), niazimicin (3) and niaziminin A + B (4 + 5). Intravenous administration of either one of the compounds (1–10 mg/kg) produced hypotensive and bradycardiac effects. The data indicates that spasmolytic activity exhibited by the constituents of the plant provides a scientific basis for the traditional uses of the plant in gastrointestinal motility disorders.