Malnutrition remains one of the world's most serious and neglected health problems worldwide. These studies explore moringa's impressive nutritional profile and its potential to enable a food-secure future.
Nutritional and clinical rehabilitation of severely malnourished children with Moringa oleifera Lam. leaf powder in Ouagadougou (Burkina Faso). Food and Nutrition, 4, 991-997. Zongo, U., Zoungrana, S. L., Savadogo, A., & Traoré, A. S. (2013).
This study shows that a daily dose of 10 grams of moringa leaf powder speeds the recovery of severely malnourished children. The use of moringa supplement significantly improved key health parameters in children aged 6-59 months, including a higher average weight gain, with no occurrence of digestive disorders.
Moringa oleifera: a review of the medical evidence for its nutritional, therapeutic, and prophylactic properties. Part 1. Trees for life Journal, 1(5). Fahey, J. W. (2005).
Jed W. Fahey, Sc.D., a nutritional biochemist who has studied moringa’s phytochemicals for almost a decade, discusses some of the tree’s most intriguing features, describing it as a "nutritional and medical cornucopia."
Investigating of Moringa Oleifera Role on Gut Microbiota Composition and Inflammation Associated with Obesity Following High Fat Diet Feeding. Open access Macedonian journal of medical sciences, 6(8), 1359. Elabd, E. M. Y., Morsy, S. M., & Elmalt, H. A. (2018).
Findings suggest that Moringa oliefera aqueous leaf extract contribute towards the pathophysiological regulation of weight gain and inflammation associated with high-fat-induced-obesity through gut bacteria modulation.
Collaboration between ISHS, GHI and the World Vegetable Center in response to world poverty and malnutrition and the role of moringa as a nutrient rich food. In I International Symposium on Moringa 1158 (pp. 11-14). Drew, R. A. (2015).
This publication from the International Society for Horticultural Science (ISHS), delivered at the 1st International Symposium on Moringa, promotes the use of moringa as a staple crop with the potential to address problems of poverty and malnutrition, citing its high levels of protein, nutrients and vitamins.
Nutritional value and antinutritional components of whole and ethanol extracted Moringa oleifera leaves. Animal Feed Science and Technology, 63(1), Makkar, H. P. S., & Becker, K. (1996).
This study concludes that moringa has an exceptionally high protein content and contains all essential amino acids. It also demonstrates that moringa extract offers a rich source of growth-promoting elements that are easily digested and metabolized in farm animals.
Nutritional characterization of Moringa (Moringa oleifera Lam.) leaves. African Journal of Biotechnology,10(60), 12925e12933 Moyo, B., Masika, P. J., Hugo, A., & Muchenje, V. (2013).
This study assesses the nutritional value of moringa leaves, and concludes that they are rich in protein, minerals, vitamins, fibers, amino acids, fatty acids and bioactive compounds.
This study evaluated the impact of the level of supplementation of Moringa oleifera leaves on the nutritional (proximate, mineral and vitamin content) as well as on the antioxidant capacities of smoothies made from a blend of pineapple, banana and apple. While supplementation with Moringa oleifera leaves offer a potential avenue to obtain additional nutrients and antioxidative properties.
Moringa Malunggay Philippines, Luis R.Villafuerte, Lalaine Villafuerte-Abonal, AG Publishing 2009
Miracle Tree, Monica G. Marcu Pharm.D., PH.D., Soundconcepts, (2013).
Moringa, Nature's Medecine cabinet, Sanford Holst, Sierra Sunrise Publishing, (2000).
The Miracle Tree, Moringa Oleifera: Natural Nutrition for the Tropics, Lowell J.Fuglie, regional representative, Church World Service, Dakar, Senegal; Moringa Tree project, Church World Service, (1999).
Measurement of sympatholytic activity of Moringa oleifera. New Trends in Natural, Products Chemistry [6 th International Symposium on Natural Products Chemistry] 269- 277. Harwood Amsterdam. Hameed-Un-Nisa L, D Shehnaz, and S Faizi. (1998).
NCTO1410058; Moringa Oleifera - Antiretroviral pharmacokinetic drug interaction. Sponsor: University of Zimbabwe; Status: Completed (Aug 2013).
This study is conducted to determine if antiretroviral drugs are affected by taking herbs at the same time. This is important because herbal medicines may interact with modern medicine to increase or decrease the amount of medication in the body. Nevirapine and efavirenz are studied. Both drugs are routinely used as part of combination therapy for treating HIV. In this study it will be determined whether the concentrations of the antiretroviral drugs nevirapine and efavirenz are low, high or are in the desired range when taken together with the herb moringa.
-->Monera-Penduka TG, Maponga CC, Wolfe AR, Wiesner L, Morse GD, Nhachi CF. Effect of Moringa oleifera Lam. leaf powder on the pharmacokinetics of nevirapine in HIV-infected adults: a one sequence cross-over study. AIDS Res Ther. 2017 Mar 14;14:12. doi: 10.1186/s12981-017-0140-4. eCollection 2017.
-->Monera-Penduka TG, Maponga CC, Morse GD, Nhachi CFB. Capacity for ethical and regulatory review of herbal trials in developing countries: a case study of Moringa oleifera research in HIV-infected patients. J Pharm Policy Pract. 2017 Feb 20;10:9. doi: 10.1186/s40545-017-0099-5. eCollection 2017.
NCT03026660; Moringa Oleifera on Bone Density. Sponsor: Appalachian State University, USA; Status: Completed (January 20, 2017).
The purpose of this study is to determine the effects of Moringa Oleifera on the structure and function of bone in post-menopausal women ingesting 1000 mg of Moringa Oleifera daily for 12 weeks.
-->Singh V, Singh N, Pal US, Dhasmana S, Mohammad S, Singh N. Clinical evaluation of cissus quadrangularis and moringa oleifera and osteoseal as osteogenic agents in mandibular fracture. Natl J Maxillofac Surg. 2011 Jul;2(2):132-6. doi: 10.4103/0975-5950.94466.
NCT02021799; The effect of under-nutrition on the human microbiota. Sponsor: Western University, Canada; Status: Completed (Dec. 2013).
The purpose of this study is to determine whether a difference exists in the gut, oral, vaginal and human milk microbiome of under-nourished pregnant women as compared to healthy and obese pregnant women. In addition, the investigators are setting out to determine if a micronutrient enriched probiotic yogurt can improve the microbiome and pregnancy outcomes of under-nourished pregnant women.
-->Bisanz JE, Enos MK, Mwanga JR, Changalucha J, Burton JP, Gloor GB, Reid G. Randomized open-label pilot study of the influence of probiotics and the gut microbiome on toxic metal levels in Tanzanian pregnant women and school children. MBio. 2014 Oct 7;5(5):e01580-14. doi: 10.1128/mBio.01580-14.
NCT02308683; Effects of Moringa Oleifera on hsCRP and Hgba1c level of patients in oSPITAL NG Maynila medical center diabetic clinic; status: Completed (Dec 2014)
Current evidence supports a central role of inflammation in the pathogenesis of atherosclerosis and diabetes [57-60]. Diabetes Mellitus (DM) type 2 is an inflammatory atherothrombotic condition associated with high prevalence of thrombotic cardiovascular disease. Among the DM risk factors (like hypertension, atherogenic dyslipidemia, insulin resistance, impaired fibrinolysis, inflammatory profile), definitely, inflammation is the neglected one. Moringa oleifera has been suggested to exert anti-inflammatory effects and hypoglycemic property. This trial investigates the effects of Moringa oleifera leaves supplementation on levels of inflammatory marker specifically hsCRP, hgbA1c level and clinical outcome in diabetic patients through a cohort study.
NCT03366922; Evaluation of Artemisia Annua and Moringa. Sponsor: Mbarara University of Science and Technology; Status:Not yet recruiting (December 8, 2017)
The objective is to determine the effect of A.annua L and Moringa oleifera leaf powder on CD4 cell count and other immunological indices in HAART HIV patients.
Expected benefits: Adequate immunological recovery is one of the desired outcomes in HIV care. HAART combinations do not directly aid immunological recovery and some patients fail to have adequate immunological recovery despite adequate suppression of viral load. There are many patients using herbal supplements but there is limited scientific clinical evidence on the benefit of these supplements in HAART patients.
NCT03019458; MINGO supplemental trial in X-linked dystonia-Parkinsonism patients (MINGO). Posted Jan 9, 2017; Status, Now Enrolling
To see whether MINGO, a food supplement containing Moringa Oleifera, will be able to lessen the drastic weight loss seen among X-linked Dystonia Parkinsonism patients.